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This can lead to low levels of glutathione, which can then lead to further health problems

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Conversely, the extrinsic pathway of apoptosis is initiated by the binding of death ligands to death receptors, which activates downstream effector caspase-8, ultimately resulting in the activation of caspase-3, -6, and 7, thereby inducing direct cell death [94]

It is most effective when used alongside professional periodontal scaling and root planing, not as a standalone intervention